Scott Downey
Well-Known Member
Honest truth is we already have several good drugs doctors can use to wipe out this coronavirus, it just has to be proven to work, but these already approved drugs could be used off label now.
Georgia State University uncovers a promising treatment for COVID-19
Like all viruses, COVID-19 cannot self-reproduce. It needs host cells — animal or human — in order to make copies of itself.
“Effective drugs need to interfere with this replication process, shutting down the virus’ ability to proliferate inside the host,” says Hussin Rothan, a co-author of the study.
With auranofin, the coronavirus was cut down by 95% in human cells within 48 hours, and inflammation caused by the disease was significantly mitigated.
One of the primary causes of death in COVID-19 patients is a syndrome called a “cytokine storm,” wherein the body’s healing response to illness goes haywire, causing immune cells to attack healthy tissue, leading to organ failure. Cells treated with auranofin, however, saw a significant drop in cytokines, the proteins that signal immune cells to attack.
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Ebola drug Remdesivir effective in treating coronavirus, Gilead Sciences data finds
“This shows that the drug not only could inhibit replication of SARS-CoV-2, mitigating the infection, but also reduce the associated lung damage that often leads to severe respiratory distress and even death,” says Kumar.
Auranofin, including the brand-name drug Ridaura, was approved by the FDA in 1985. The drug is unique for being partially composed of gold particles, which have been used for centuries for their anti-inflammatory properties. Treatments involving gold compounds have also been considered for use against HIV, cancer, neurodegenerative disorders, and parasitic and bacterial infections.
Georgia State University uncovers a promising treatment for COVID-19
Like all viruses, COVID-19 cannot self-reproduce. It needs host cells — animal or human — in order to make copies of itself.
“Effective drugs need to interfere with this replication process, shutting down the virus’ ability to proliferate inside the host,” says Hussin Rothan, a co-author of the study.
With auranofin, the coronavirus was cut down by 95% in human cells within 48 hours, and inflammation caused by the disease was significantly mitigated.
One of the primary causes of death in COVID-19 patients is a syndrome called a “cytokine storm,” wherein the body’s healing response to illness goes haywire, causing immune cells to attack healthy tissue, leading to organ failure. Cells treated with auranofin, however, saw a significant drop in cytokines, the proteins that signal immune cells to attack.
SEE ALSO
Ebola drug Remdesivir effective in treating coronavirus, Gilead Sciences data finds
“This shows that the drug not only could inhibit replication of SARS-CoV-2, mitigating the infection, but also reduce the associated lung damage that often leads to severe respiratory distress and even death,” says Kumar.
Auranofin, including the brand-name drug Ridaura, was approved by the FDA in 1985. The drug is unique for being partially composed of gold particles, which have been used for centuries for their anti-inflammatory properties. Treatments involving gold compounds have also been considered for use against HIV, cancer, neurodegenerative disorders, and parasitic and bacterial infections.
