The question is whether someone who has been sanctified can then trample the Son of God uderfoot.
Many Presbyterians say "yes." Infants, they say, are sanctified by baptism, set apart to God, but yet can fall away. This argument comes up on the Puritan Board regularly. I hope that as a Baptist you would reject such an argument out of hand.. Believers are Christ's sheep; they hear His voice and they follow Him. And Christ will never let them fall away so as to trmple Him underfoot. No, it is the unbeliever who may take a temporary interest in Christianity (c.f. Matthew 13:20-22) who by falling away may be described as trampling the Son of God underfoot.
It is the Presbyterian bias in some translations that keep them from capitalizing 'he.' Interestingly the famous John Owen, when he wrote Death of Death in the Death of Christ as a young man and a Presbyterian, followed the Presby line, but later when, as a Congregationalist he wrote his mammoth commentary on Hebrews, he had come to see that sanctified believers cannot fall awway and changed his view.
(ABPs+) Of how muchG4214 do you thinkG1380 worseG5501 shall he be worthy ofG515 punishmentG5098 the oneG3588 [2theG3588 3sonG5207 G3588 4of GodG2316 1having trampled],G2662 andG2532 [2theG3588 3bloodG129 4of theG3588 5covenantG1242 6as commonG2839 1esteeming],G2233 inG1722 whichG3739
he was sanctified,G37 andG2532 [2theG3588 3spiritG4151 G3588 4of favorG5484 1having insulted]?G1796
(BSB 1.2) How much more severely do you think one deserves to be punished who has trampled on the Son of God, profaned the blood of the covenant
that sanctified him, and insulted the Spirit of grace?
(CJB) Think how much worse will be the punishment deserved by someone who has trampled underfoot the Son of God; who has treated as something common the blood of the covenant
which made him holy; and who has insulted the Spirit, giver of God's grace!
(ESV+) How much worse punishment, do you think, will be deserved by the one R11who has trampled underfoot the Son of God, and has profaned R12the blood of the covenant R13
by which he was sanctified, and has R14outraged the Spirit of grace?
(LEB Q) How much worse punishment do you think the person will be considered worthy of who treats with disdain the Son of God and who considers ordinary the blood of the covenant
by which he was made holy and who insults the Spirit of grace?
(NET+) How much greater punishment do you think that person deserves who has contempt forN35 the Son of God, and profanesN36 the blood of the covenant
that made him holy,N37 and insults the Spirit of grace?
(NIV 1984) How much more severely do you think a man deserves to be punished who has trampled the Son of God under foot, who has treated as an unholy thing the blood of the covenant
that sanctified him, and who has insulted the Spirit of grace?
(NKJV) Of how much worse punishment, do you suppose, will he be thought worthy who has trampled the Son of God underfoot, counted the blood of the covenant
by which he was sanctified a common thing, and insulted the Spirit of grace?
(NLTs) Just think how much worse the punishment will be for those who have trampled on the Son of God, and have treated the blood of the covenant,
which made us holy, as if it were common and unholy, and have insulted and disdained the Holy Spirit who brings God's mercy to us.
(NRSV) How much worse punishment do you think will be deserved by those who have spurned the Son of God, profaned the blood of the covenant
by which they were sanctified, and outraged the Spirit of grace?
After all these there is only one question that has to be answered. Was Christ Jesus made Holy by the blood of the covenant, His death and resurrection or was the one who trusted in Christ Jesus the one who was made Holy?
From reading the text as we find it, it would seem that yes man can repudiate the faith that they once held.