vaccine is needed
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CORONAVIRUS Cure?
- Thread starter HankD
- Start date
Scott Downey
Well-Known Member
Chloroquine stops the virus from binding to the cell membrane.
Remdesivir mimics viral adenosine one of the viral mRNA molecules, and it gets built into the virus duplication and stops viral replication. In effect it jams up the works.
Remdesivir is an adenosine analogue, which incorporates into nascent viral RNA chains and results in pre-mature termination, the drug has been around for a decade now.
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
“Treatment with intravenous remdesivir was initiated on the evening of day 7, and no adverse events were observed,” the medical team wrote in a case report in the New England Journal of Medicine. The man started feeling better the following day.
With the coronavirus, drug that once raised global hopes gets another shot
Remdesivir mimics viral adenosine one of the viral mRNA molecules, and it gets built into the virus duplication and stops viral replication. In effect it jams up the works.
Remdesivir is an adenosine analogue, which incorporates into nascent viral RNA chains and results in pre-mature termination, the drug has been around for a decade now.
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
“Treatment with intravenous remdesivir was initiated on the evening of day 7, and no adverse events were observed,” the medical team wrote in a case report in the New England Journal of Medicine. The man started feeling better the following day.
With the coronavirus, drug that once raised global hopes gets another shot
Scott Downey
Well-Known Member
A vaccine is very important, but this drug combo will work even on mutated corona viruses. A virus cant mutate but so far before it can no longer invade a cell.
Another treatment is created artificial antibodies, something your own body given enough time does to destroy an infection.
Regeneron: potential Covid-19 drugs could start human tests this summer
Another treatment is created artificial antibodies, something your own body given enough time does to destroy an infection.
Regeneron: potential Covid-19 drugs could start human tests this summer
Scott Downey
Well-Known Member
Bayer donates millions of tablets of chloroquine to help in COVID-19 fight
Baxtor can make many more pills easily too.
Baxtor can make many more pills easily too.
Dave G
Well-Known Member
It will be over soon.
Treatment or no treatment, the Spanish Flu of 1918 burned itself out in roughly 2-3 months, and it was far worse than this virus.
Look at some of the statistics:
Coronavirus Update (Live): 255,943 Cases and 10,496 Deaths from COVID-19 Virus Outbreak - Worldometer
In addition, we as believers have a God that still answers prayers, many times miraculously.
Let us look to Him and His promises, and trust Him ( Proverbs 3:5-7 ).
After what he has done for us, He deserves our trust.
Treatment or no treatment, the Spanish Flu of 1918 burned itself out in roughly 2-3 months, and it was far worse than this virus.
Look at some of the statistics:
Coronavirus Update (Live): 255,943 Cases and 10,496 Deaths from COVID-19 Virus Outbreak - Worldometer
In addition, we as believers have a God that still answers prayers, many times miraculously.
Let us look to Him and His promises, and trust Him ( Proverbs 3:5-7 ).
After what he has done for us, He deserves our trust.
Scott Downey
Well-Known Member
Italy is starting prophylactic usage of chloroquine in normal uninfected people which they think will prevent infections. It does though have a few side effects.
Trying to flatten the curve prolongs the duration of a pandemic as it leaves vulnerable populations.
Spanish flu also mutated several times and came in 3 waves, then it never came back. Likely another final mutation rendered it unable to cause severe flu.
Trying to flatten the curve prolongs the duration of a pandemic as it leaves vulnerable populations.
Spanish flu also mutated several times and came in 3 waves, then it never came back. Likely another final mutation rendered it unable to cause severe flu.
Scott Downey
Well-Known Member
FDA: Studies Underway to Evaluate Chloroquine for COVID-19 - MPR
CURED after 6 days.
Chloroquine and azithromycin were potent together.
Recently, findings were announced from an open-label study investigating hydroxychloroquine in hospitalized patients with confirmed COVID-19 at The Méditerranée Infection University Hospital Institute in Marseille, France. Patients received oral hydroxychloroquine 200mg 3 times daily for 10 days (n=20), and those who refused were part of the control group (n=16). Patients were included if they were 12 years of age and older, and had PCR documented SARS-CoV-2 carriage in nasopharyngeal samples at admission. Treatment with antibiotics (eg, azithromycin) was also provided to patients to prevent bacterial infections. The primary end point was virological clearance at day 6 post-inclusion.
Results of the study showed that by day 6 post-inclusion, 70% of hydroxychloroquine-treated patients were virologically cured vs 12.5% in the control group (P =.001). Moreover, at day 6 post-inclusion, 100% of patients treated with hydroxychloroquine plus azithromycin were virologically cured compared with 57.1% of patients with hydroxychloroquine only and 12.5% of the control group (P <.001). A significant difference between the hydroxychloroquine and control groups was reported as early as day 3 post-inclusion.
Study investigators noted that 1 patient treated with hydroxychloroquine who was still PCR-positive at day 6 post-inclusion was given azithromycin in addition to hydroxychloroquine at day 8, and was virologically cured at day 9. Conversely, 1 patient treated with the combination therapy who tested negative at day 6, tested positive at low titer at day 8. While the results look promising, the researchers noted limitations to their study including small sample size, limited long-term outcome follow-up, and dropout of 6 patients from the study.
CURED after 6 days.
Chloroquine and azithromycin were potent together.
Recently, findings were announced from an open-label study investigating hydroxychloroquine in hospitalized patients with confirmed COVID-19 at The Méditerranée Infection University Hospital Institute in Marseille, France. Patients received oral hydroxychloroquine 200mg 3 times daily for 10 days (n=20), and those who refused were part of the control group (n=16). Patients were included if they were 12 years of age and older, and had PCR documented SARS-CoV-2 carriage in nasopharyngeal samples at admission. Treatment with antibiotics (eg, azithromycin) was also provided to patients to prevent bacterial infections. The primary end point was virological clearance at day 6 post-inclusion.
Results of the study showed that by day 6 post-inclusion, 70% of hydroxychloroquine-treated patients were virologically cured vs 12.5% in the control group (P =.001). Moreover, at day 6 post-inclusion, 100% of patients treated with hydroxychloroquine plus azithromycin were virologically cured compared with 57.1% of patients with hydroxychloroquine only and 12.5% of the control group (P <.001). A significant difference between the hydroxychloroquine and control groups was reported as early as day 3 post-inclusion.
Study investigators noted that 1 patient treated with hydroxychloroquine who was still PCR-positive at day 6 post-inclusion was given azithromycin in addition to hydroxychloroquine at day 8, and was virologically cured at day 9. Conversely, 1 patient treated with the combination therapy who tested negative at day 6, tested positive at low titer at day 8. While the results look promising, the researchers noted limitations to their study including small sample size, limited long-term outcome follow-up, and dropout of 6 patients from the study.
Sure hard not to be optimistic at this point.
Gold Dragon
Well-Known Member
It is more likely that by the 3rd wave, most humans in the world were either dead or immune and it did not mutate enough to get past our immune systems. Without a human reservoir or another animal reservoir, it was eradicated.
Scott Downey
Well-Known Member
Absolutely, NYS is starting to use Chloroquine, but they should do this just as France did. The sooner people get well, the better. then the fear mongering media can shut up.
Gold Dragon
Well-Known Member
I posted the France study that was still awaiting review a couple of days ago. While the results were promising, it was a very small and not an ideally designed study. In other words, the results are hard to put too much faith in at this time.
But it was a great study to then launch into what the US is doing with larger, better designed studies (that produce more robust and reproducible results) that require lots of funding to organize. We will see soon how effective those therapies are.
Some causes for concern are that Italy has already been using hydroxychloroquine and chloroquine and azithromycin and they are still getting overrun. There are some reports they already gave up on azithromycin being effective.
However they were probably using it on much sicker patients than the French group and may not have been using them together.
Things moving fast with this drug. I'm guardedly optimistic, but not overly. Very curious why Italy is not having success, but they seem to be the anomaly of the planet. China really bulled them into keeping their border open, and they're paying the price. I do pray they find a solution soon.
Hospitals Begin Stockpiling Hydroxychloroquine Following Announcement of its Success Rate in Battling Coronavirus
Israeli Pharmaceutical Company Donates 6 Million Doses of Chloroquine to US to treat Coronovirus
Hospitals Begin Stockpiling Hydroxychloroquine Following Announcement of its Success Rate in Battling Coronavirus
Israeli Pharmaceutical Company Donates 6 Million Doses of Chloroquine to US to treat Coronovirus
Might Italy's issues transcend the Corona Virus?
Report: Italian Adviser Suggests that Coronavirus Death Rates in Italy may be Exaggerated
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Gold Dragon
Well-Known Member
Might Italy's issues transcend the Corona Virus?
Report: Italian Adviser Suggests that Coronavirus Death Rates in Italy may be Exaggerated
I would say that is a politician trying to massage the data to give the impression to the public and the world that things are not as bad as they seem. But they are that bad.
If you have ever written a death certificate before, "direct causality" is often cardiac or respiratory failure because for everyone who dies, they die because their heart stops or their lungs stop working. I have been reading reports that many covid19 ICU patients are actually dying of heart attacks while fighting off covid19. So should you not consider covid19 the cause of death if they never would have had that heart attack without covid19?
This is just a politician trying to play with the numbers.
Also this is a known consequence of what happens when your hospital system gets overrun. Many people who would normally get quality medical care and survive will end up dying because the system is overrun.
Did coronavirus cause those deaths as well? There is definitely an argument that this is a valid way to code their death and it is something that is not easy to parse out who would or would not have survived if the epidemic were not happening.
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Scott Downey
Well-Known Member
Several ways chloroquin works.
It suppresses the immune system so that patient does not develop a inflammatory cytokine storm. Young children dont get affected because their undeveloped immune system can not mount such a storm. The old people immune response to covid - 19 is so powerful it causes their death due to their lungs becoming fluid filled with that over response.
Cytokine storm syndromes (CSS) are a group of disorders representing a variety of inflammatory causes. The primary symptoms of a cytokine storm are high fever, swelling and redness, extreme fatigue and nausea. In some cases the immune reaction may be fatal.
It prevents entry of virus into the cell.
It creates a hole in the virus which ZINC latches onto and the zinc makes it inert. Take ZINC supplements to help stop cold viruses and this one is a good idea.
More info on this, and it is good to see the French cure study being taken seriously, they are going to replicate that, in NY.
Toxicologist says anti-malaria drugs show 'promise' in treating coronavirus
It suppresses the immune system so that patient does not develop a inflammatory cytokine storm. Young children dont get affected because their undeveloped immune system can not mount such a storm. The old people immune response to covid - 19 is so powerful it causes their death due to their lungs becoming fluid filled with that over response.
Cytokine storm syndromes (CSS) are a group of disorders representing a variety of inflammatory causes. The primary symptoms of a cytokine storm are high fever, swelling and redness, extreme fatigue and nausea. In some cases the immune reaction may be fatal.
It prevents entry of virus into the cell.
It creates a hole in the virus which ZINC latches onto and the zinc makes it inert. Take ZINC supplements to help stop cold viruses and this one is a good idea.
More info on this, and it is good to see the French cure study being taken seriously, they are going to replicate that, in NY.
Toxicologist says anti-malaria drugs show 'promise' in treating coronavirus
Hobie
Well-Known Member
Yes, hydroxychoroquine, sold under its brand name Plaquenil. This however is for those who are really bad, as there are side effects.
Plaquenil Uses, Dosage & Side Effects - Drugs.com
I get that. It's just that Italy seems to be an anomaly. Yes, things are bad, but it also sounds like there is some chaos in the government that's being exposed and maybe data collecting is part of that.
We know the WHO is a mess and listened to China way too much, spending false information. We know China has lied about this epidemic, even lied about the source of it, blaming it on the US military. When you have anomalies in the data like we see from Italy, human error has to at least be considered, I would think.
You say this as if there are no politicians in Italian leadership. I'm just as skeptical of politicians. It just seems we're trusting in different ones. When you have one group of politicians running things in one country that's an anomaly, it seems you should question them first, rather than questioning all the others. I'm tending to side with the whistleblower in this case.
This is not an issue of medial knowledge, but common sense.