The Bible tells us that the one doing the action is the Creator, the action is creating, and the result is the creation. Since God created the Heavens and the Earth, we must infer whether all of creation, i.e. the Universe, or some lesser part of creation, i.e. a born anew believer is in view. If the context points to a specific creation, perhaps using a less general term might help us better understand the word of God.
Mark 10:6 (NASB) But from the beginning of creation,
God MADE THEM MALE AND FEMALE.
Here our choices are (1) the whole Universe or (2) humankind. Contextually humankind is the creation in view. So would not the actual intended message be "But from the beginning of humankind, God made them male and female?
Mark13:19 “For those days will be a
time of tribulation such as has not occurred since the beginning of the creation which God created until now, and never will.
Here, again, tribulation refers to the hard times humankind will endure, and thus creation refers to humankind.
Mark16:15 And He said to them, “Go into all the world and preach the gospel to all creation.
The creation in view again is humankind.
Romans 1:20
For since the creation of the world His invisible attributes, His eternal power and divine nature, have been clearly seen, being understood through what has been made, so that they are without excuse.
Here another New Testament writer (Paul) uses the phrase "creation of the world" to refer to the creation of humankind. Since the "creation" is specifically identified, "creation of humankind" better conveys the message. Clearly only humankind could see using some spiritual ability God's eternal power and divine nature.
Romans 1:25 For they exchanged the truth of God for a lie, and worshiped and served the creature rather than the Creator, who is blessed forever. Amen.
Here it is not clear (at least to me) just what is being worshiped and served as if divine. Satan, idols made by hand, physical gratification all might be in view. I think "the creation" leaves open God's message.
Romans 8:19 For the anxious longing of the creation waits eagerly for the revealing of the sons of God.
But here again, humankind is in view.
Romans 8:20 For the creation was subjected to futility, not willingly, but because of Him who subjected it, in hope
Once again we see humankind is in view. Those that think something more is in view cannot explain how those other things could "hope."